database.name

What exists, and how to get in.

Mechanism and Catalytic Site Atlas

Also known as CSA (formerly) · formerly: Catalytic Site Atlas · M-CSA

M-CSA is a database of enzyme reaction mechanisms. It provides annotation on the protein, catalytic residues, cofactors, and the reaction mechanisms of hundreds of enzymes. There are two kinds of entries in M-CSA. 'Detailed mechanism' entries are more complete and show the individual chemical steps of the mechanism as schemes with electron flow arrows. 'Catalytic Site' entries annotate the catalytic residues necessary for the reaction, but do not show the mechanism. The M-CSA (Mechanism and Catalytic Site Atlas) represents a unified resource that combines the data in both MACiE and the CSA

Getting access

Open access Open

How to apply
Not yet verified — we don’t publish a route we haven’t checked.

Summarised from a registry — the exact application route is not yet verified.

About this database

Websitehttps://www.ebi.ac.uk/thornton-srv/m-csa/search/
SubjectsLife Sciences · Natural Sciences · Biology · Medicine · Chemistry · Basic Biological and Medical Research · Analytical Chemistry, Method Development (Chemistry) · Biochemistry · Bioinformatics and Theoretical Biology
Last updated2026-09-11

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